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KMID : 0358419960390020365
Korean Journal of Obstetrics and Gynecology
1996 Volume.39 No. 2 p.365 ~ p.373
Relationship of Endometrial Thickness and Pattern to Pregnancy Rate in Superovulation with Intrauterine Insemination Cycles
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Abstract
The purpose of present study was to determine if the endometrial thickness and pattern are related to clinical pregnancy rate in patients undergoing superovulation with intrauterine insemination(IUI). Endometrial thickness and pattern was
evaluated
prospectively in 59 cycles of superovulation with IUI, between May 1994 and July 1995. On the day of human chorionic gonadotropin(hCG) administration, endometrial thickness and pattern were assessed with an ultrasound equipped with a 5 MHz
vaginal
probe. There was no correlation between serum estradiol and endometrial thickness. There was a significant correlation between endometrial thickness and clinical pregnancy rate in patients group with endometrial thickness<17 mm. Clinical
pregnancy
rate
was significantly increased when the endometrial thickness was ¡Ã11mm (p<0.05). Endometrial pattern A(a 'triple line' multilayer) was observed in 42 cycles(71.1%), pattern B(isoechogenic) in 11 cycles(18.6%), and pattern C(hyperechogenic) in 6
cycles(10.2%). There was no significant difference in the clinical pregnancy rate between the group with endometrial pattern A and the group with endometrial pattern B or C. In patient group with endometrial pattern A, the clinical pregnancy rate
was
significantly higher for endometrial thickness ¡Ã11mm than for endometrial thickness <11 mm. However, in the patient group with endometrial pattern B and C, there was no difference in clinical pregnancy rate between the group with endometrial
thickness¡Ãmm and <11 mm. This study suggests that ultrasonographic analysis of endometrial thickness on the day hCG administration has a predictive value for pregnancy in superovulation with IUI cycles.
KEYWORD
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